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--- Did Tony win the game?
--- No. Staying up late made him at his worst _____ physical situation.
A．in case ofB．in terms ofC．in favor ofD．in spite of
B

試題分析：A. in case of如果，萬一，B. in terms of 就…而言，C. in favor of支持，贊同，D. in spite of雖然，句意：—Tony贏得了比賽嗎？--沒有熬夜使他就身體狀況而言是最糟糕的。所以選B。
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