_____ great efforts, we failed to carry our plans through, which made us very disappointed.
A．In place ofB．Instead ofC．In case ofD．In spite of
D

試題分析：考查短語辨析。A代替，取代；B而不是；C以防，萬一；D盡管。句意：盡管我們作出了巨大努力,我們還是沒能完成計劃，使得我們非常失望。根據(jù)句意說明D正確。
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