It’s uncertain _______ side effect the medicine will bring about , although about two thousand patients have taken it ．
A．thatB．whatC．howD．whether
B
考查賓語從句，it 做形式賓語，真正的賓語是后面的從句，而從句中bring about后缺少賓語，故用what,what又做定語修飾side effect，所以選B。
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