-- - Alison, I’m sorry. I can’t come to the wedding with you tomorrow morning. 
   -- ________? 
   -- My grandma was severely ill, so I have to stay in the hospital to look after her. 
A．How is itB．How comeC．So whatD．What’s the problem
B
這題考查交際用語：How come怎么回事？So what那又怎樣？ What’s the problem問題是什么？，根據(jù)句意：--對不起，Alison，每天早晨我不能和你參加婚禮了。--怎么了？--我奶奶病的厲害，我要在醫(yī)院照顧她。選B。
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