He tried his best to solve the problem, 　　　　difficult it was.  

A. no matter whatB. whateverC. howeverD. how

 

C

【解析】

試題分析：考查狀語從句。句意：他努力去解決這個問題，無論它有多么的困難。后半句是讓步狀語從句，however相當(dāng)于no matter how 后面跟形容詞或副詞,而whatever 等于no matter what后面跟名詞，故選C項。

考點 : 考查狀語從句

 

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