100.5×27-0.5×27．

解：100.5×27-0.5×27，
=（100+0.5）×27-0.5×27，
=100×27+0.5×27-0.5×27，
=100×27，
=2700．
或（100.5-0.5）×27，
=100×27，
=2700．
分析：把100.5寫作100+0.5，利用乘法分配律展開，即可得解．
點(diǎn)評：此題考查了運(yùn)算定律與簡便運(yùn)算．
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